Excessive alcohol use causes about 178,000 deaths annually in the U.S., with two-thirds from chronic conditions like liver disease and cancer, and one-third from acute incidents like overdoses and accidents. Alcohol-related deaths have increased significantly, with men accounting for 67.1% of these deaths. SOURCE
The death toll has risen 29% in five years
Federal data tracks approximately 178,000 Americans dying from excessive alcohol each year — equivalent to one death every three minutes, around the clock. That toll rose 29% between 2016–17 and 2020–21, climbing from an average of 137,927 annual deaths to 178,307. The pace has accelerated sharply: deaths jumped 23% in the most recent measured period, nearly four times the 5% rate recorded in the prior years.
Women represent the fastest-growing group. Female alcohol-related deaths climbed 35% over this period, outpacing the 27% rise among men.
These deaths are not just premature — they are dramatically premature. On average, each person who dies from excessive alcohol use loses 24 years of potential life. Across the full death toll, that amounts to approximately 4 million years of potential life lost every year in the United States.
The five leading causes are alcohol-associated liver disease, heart disease and stroke, accidental poisonings (including combined alcohol-drug overdoses), falls and crashes, and alcohol-related cancers — particularly colorectal and breast cancer. Alcohol now accounts for 44.5% of all liver disease deaths in the United States, and contributes to roughly 5.6% of all US cancer cases.
Alcohol also plays a significant role in other forms of violent and accidental death. In 2022, alcohol was a factor in approximately 16% of drug overdose deaths, and an estimated 21% of suicide decedents had a blood alcohol concentration of 0.10% or higher at the time of death. SOURCE
